Last Updated: 19/06/2024
Search for a non-resistant antimalaria treatment targeting erythrocyte semaphorin 7A
Objectives
*Original title and abstract were machine translated from Japanese.
To verify the role of S7A in the pathogenesis of malaria and find out whether it is possible to reduce pathogenicity by suppressing the function of S7A.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
The lack of effective prevention and treatment for malaria is due to the acquisition of resistance to protozoans, which requires a shift from traditional strategies targeting protozoans. The preliminary experimental results strongly suggest that the semaphorin 7A protein (S7A) inherent in host erythrocytes may play an important role in the pathogenicity of malaria.
External reference
Themes
Date
Apr 2022 — Mar 2025
Total Project Funding
$35,000
Funding Details
Country / Project Site(s)
Related Resources
