Search for anti-malaria parasite active substances targeting “heme polymerization” from microbial culture fluid

Objectives

*Original title and text were machine translated from Japanese.

In this application, microbial culture fluids were screened using the inhibitory activity of the malaria parasite’s detoxification system “heme polymerization” as an indicator in order to discover seed compounds for the development of malaria treatment drugs that can be supplied to patients and can be administered orally.