Last Updated: 18/06/2024

New aminobenzimidazole antimalarial agents with a novel mechanism of action

Objectives

This project seeks to identify the novel mechanism of action responsible for the activity of a new class of aminobenzimidazole antimalarials.

Principal Institution

Monash University (MON), Australia

Principal Investigators / Focal Persons

Darren Creek

Rationale and Abstract

Malaria is a disease with a globally significant burden and distribution, including a presence in Australia’s northern neighbours East Timor, Indonesia and Papua New Guinea. Resistance to all major classes of antimalarial drugs has emerged in Asia in the last decade, meaning new antimalarials with unique mechanisms of action are urgently needed.

Date

Jan 2019 — Dec 2021

Total Project Funding

$533,507

Project Site

Australia

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