Last Updated: 18/06/2024

Investigation of dendritic cell activation and function in a murine model of Plasmodium and Schistosoma co-infection

Objectives

The aim of this project is to investigate how malaria and worm parasites interact to influence the immune response and clinical outcomes of each other in a mouse infection model.

Principal Institution

Burnet Institute, Australia

Principal Investigators / Focal Persons

Rachel Lundie

Rationale and Abstract

Malaria is responsible for over 2 million deaths annually, mainly in sub-Saharan Africa. Importantly, around 1 billion people in malaria endemic areas are infected with parasitic worms, thus malaria and worm co-infections frequently occur. This will provide new strategies for the design of effective treatments in co-endemic areas.

Date

Jan 2009 — Dec 2015

Total Project Funding

$327,266

Country / Project Site(s)

Australia

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