Last Updated: 01/10/2025
Construction of a new “delayed death” model by splitting lipid convertase
Objectives
The purpose of this research project is to construct a new model for the occurrence of “delayed death” caused by a deficiency in lipid conversion enzymes expressed at the schizont stage.
Known “delayed death” is known to be caused by molecular defects expressed in the trophozoite stage of the parasite. This study will clarify whether “delayed death” caused by a deficiency in lipid conversion enzymes at the schizont stage is caused by the same mechanism as the existing model or an unknown mechanism. Through this study, the researchers aim to deepen their understanding of the molecular mechanism that causes “delayed death” in malaria parasites and to gain further insight into the parasite’s parasitism and proliferation mechanisms.
Dec 2022 — Mar 2025
$32,030