Last Updated: 08/07/2025
The role of novel and essential bromodomain proteins in coordinating malaria parasite gene regulation and their potential as anti-malarial targets
Objectives
This project will characterise a novel group of proteins to identify those that activate genes essential for parasite survival.
Principal Institution
Principal Investigators / Focal Persons
Partner Investigators
Rationale and Abstract
Malaria kills over 400,000 people a year and new therapies are needed. Malaria parasites activate groups of genes by novel mechanisms that could be targeted by drugs. This project will also search for molecules that inhibit the proteins and kill malaria parasites. Thus it will enable the discovery of how parasites control their genes and identify drug targets and inhibitors for drug development.
External reference
Themes
Date
Jan 2017 — Dec 2019
Total Project Funding
$507,115
Funding Details
National Health and Medical Research Council (NHMRC) Australia, Australia
Grant ID: 1128975
AUD 689,034
Project Site
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