Last Updated: 12/12/2025

Targeting commitment to sexual differentiation in Plasmodium

Objectives

This project will develop urgently needed strategies to target gametocytes, and thus block malaria transmission.

Principal Investigators / Focal Persons

Leann Tilley

Partner Investigators

Matthew Chico
Malcolm McConville

Rationale and Abstract

Efforts to control malaria in endemic areas are very often thwarted by ‘carriers’, who have transmissible parasites in their bloodstream (called gametocytes), but who suffer no symptoms. These gametocytes serve as a reservoir ready to reinitiate disease transmission when mosquito numbers increase.

Date

Jan 2016 — Dec 2018

Total Project Funding

$518,095

Country / Project Site(s)

Australia

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