Last Updated: 20/03/2026
Breaking malaria’s lethal grip: Targeting the assembly of an adhesive complex on infected red blood cells
Objectives
This project will fully elucidate the pathway for trafficking of the adhesion protein to the red blood cell surface with a view to finding new ways of interfering with malaria disease.
Principal Institution
Principal Investigators / Focal Persons
Partner Investigators
Rationale and Abstract
The malaria parasite, Plasmodium falciparum, infects the red blood cells of its human victims. It causes them to stick to blood vessel walls in the brain, causing severe cerebral complications and death. Adhesion is mediated by a Velcro-like protein that is presented at the red blood cell surface.
External reference
Themes
Date
Jan 2015 — Dec 2018
Total Project Funding
$595,559
Funding Details
National Health and Medical Research Council (NHMRC) Australia, Australia
Grant ID: 1078065
AUD 792,183
Project Site
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