Last Updated: 30/06/2024
Mitishamba database of natural products from Kenyan plants for design of antimalarial drugs
Objectives
The project team sought to develop a web-based, searchable, in-silico database of natural products of Kenya, to provide knowledge and information about the rich diversity of Kenyan flora that may be used in drug discovery.
Malaria affects half of the world’s population. The hits from the virtual screen will then be synthesized and optimized for maximum antimalarial activity. The study will contribute novel templates for the discovery of antimalarial drugs. Drug discovery from natural products for diseases like malaria is both time- and cost-intensive. An efficient approach is to use computer-aided drug design (CADD) through which virtual screening investigates a virtual library of natural products from a database against biological targets linked with disease processes.
Apr 2013 — Sep 2014
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