Last Updated: 01/12/2025
Measuring changes in paediatric malaria hospitalization in Kenya, Uganda and Zambia 2000-2010
Objectives
The proposed work aims to establish whether there has been a statistically significant decline in paediatric malaria hospitalization in Kenya, Uganda, and Zambia between 2000 and 2010, and establish whether, by controlling for covariates related to climate and service use, this decline can be attributed to expanded coverage of insecticide-treated nets and new artemisinin-based combination therapies.
Reports of declining incidence of malaria hospitalization, deaths, and prevalence in several diverse areas of Africa suggest that the epidemiology of malaria is in transition across the continent. This transition has been coincidental with the scaling of intervention coverage and increased international funding for the control of malaria. However, precise attribution to intervention coverage alone remains circumstantial, not least because at most sites where declining disease incidence and prevalence have been reported, declines started before a significant increase in donor assistance and scaled intervention coverage
These questions will be tackled using a variety of time-series models applied to data from 19 hospitals located in different transmission settings across three countries, and importantly, where the scaling up of interventions has temporally varied during the observation period. Understanding the changing epidemiology of malaria in Africa should provide direct evidence of intervention impact and provide a better platform to define the progress and needs toward international development targets.
Feb 2009 — Jul 2013
$306,959
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