EMIRA: Ecologic Malaria Reduction for Africa – innovative tools for integrated malaria control

Recent malaria control and elimination attempts show remarkable success in several parts of sub-Saharan Africa. Vector control via larval source management represents a new and to date underrepresented approach in low income countries to further reduce malaria transmission. Although the positive impact of such campaigns on malaria incidence has been researched, there is a lack of data on which prerequisites are needed for implementing such programs on a routine basis on large scale.

Clinical trial id: PACTR201611001721299

The project is designed as prospective intervention study with duration of three years (2013–2015). Its spatial scale includes three arms of interventions and control, comprising a total of 127 villages and the district capital Nouna in the extended HDSS (Health Demographic Surveillance System) of the Kossi province. Baseline data on mosquito abundance, parasitemia in U5 children, and malaria related morbidity and mortality are gathered over the project duration. Besides the outcome on ecologic and health parameters, the economic costs are seized and valued against the achieved health benefits.

Mosquito species targeted and larvicide used: Anopheles gambiae s.l., A. funestus and A. nili. / Bacillus thuringiensis var. israelensis (Bti)

Pan African Clinical Trials Registry - Trial details

Vector Control

Jan 2013 — Dec 2015

Burkina Faso

Larval source management
Tracking progress against the PMI Insights Research Priorities