Last Updated: 17/11/2025

Ecology and behaviour of insecticide-resistant Aedes aegypti for dengue and other emerging arboviruses control in West Africa

Objectives

This proposal aims at characterizing the extent of insecticide resistance and the underlying mechanisms in Aedes aegypti and assessing how this may impact its behaviour and ecology.

An investigation using next-generation sequencing targeted method will be performed to assess the spatio-temporal distribution of resistance mutations across West Africa. The impact of insecticide resistance on Aedes mosquitoes’ life traits and parameters will also be evaluated. The biting and host-seeking behaviour and the environmental factors affecting this behaviour will be determined. The data generated will fill the gap in knowledge on arbovirus vectors and support the implementation of a sustainable control strategy.

Principal Investigators / Focal Persons

Kobie Hyacinthe TOE

Rationale and Abstract

There is a growing concern about the arboviruses infections testified by the recent dengue, Zika, Chikungunya and Yellow fever outbreaks in Africa. The primary response to the increase of arboviruses transmission is based on the reduction of the larval source using biological, mechanical and chemical methods and the reduction of adults which is based on the use of chemical insecticides. However, there is limited knowledge on the ecology and insecticide resistance of the primary vector Aedes mosquitoes, which is becoming resistant to multi-insecticide classes, as we reported in Burkina Faso.

Funding Details
Country / Project Site(s)

Burkina Faso

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