Last Updated: 21/11/2025
Development of vector-borne disease control method using venom expression parasite
Objectives
*Original title and text were machine translated from Japanese
The study aims to develop a new method for controlling vector-borne diseases by utilizing venom-expressing malaria parasites, addressing issues related to insecticide resistance and side effects.
Obihiro University of Agriculture and Veterinary Medicine, Japan
In vector-borne infection measures such as mosquitoes, vector control by insecticides is the most important strategy. However, the use of insecticides has various problems such as acquiring resistance and side effects. This study focused on a venom, natural poison possessed by natural enemies. There was success in producing venom-expressing malaria parasites using melittin as a model. In addition, there was success in developing a new gene recombination method for rodent malaria parasite, and it has facilitated the production of multiple mutants that were difficult to date. It was also suggested that venom-expressing parasite could be applied to vaccine development.
Apr 2016 — Mar 2019
$34,126
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