Last Updated: 19/06/2024
Chemical probes to dissect the cell cycle of globally important parasites
Objectives
To develop new reagents, called chemical probes, to visualise key biological events in globally important pathogens.
Griffith University, Australia
Robert Koch Institute (RKI), Germany
Innovative chemistry will be used to modify the building blocks of DNA and provide researchers with essential tools to ‘see’ DNA synthesis in order to study growth and replication of pathogens in combination with microscopy. This project expects to support a major technical advance that will address important gaps in our understanding of many pathogens (e.g. those that cause malaria and tuberculosis), at both the cellular and molecular levels. This should provide significant benefits by enabling researchers worldwide to identify new intervention opportunities that target unique aspects of pathogen biology.
Jan 2022 — Dec 2024
$311,044
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