Last Updated: 30/11/2025
Catalyzing the Adoption of a Novel Vector Control Toolbox (CANVeCT)
Objectives
CANVeCT project aims to further evolve the evidence-base on spatial repellents, particularly on their potential stand-alone use, generating additional evidence to inform the evolution of WHO’s recommendation for the use of spatial repellents, while also exploring their effectiveness in humanitarian settings.
Malaria remains one of the world’s deadliest diseases, especially in sub-Saharan Africa, where over 90% of global malaria deaths occur. Despite significant progress, progress has stalled. Vector control tools, such as insecticide-treated nets and indoor spraying, remain the cornerstone of malaria prevention, but their effectiveness is declining due to insecticide resistance, changing mosquito behavior, and environmental factors. New vector control tools are now more critical than ever to expand the range of effective prevention tools to protect the most vulnerable. The World Health Organization (WHO)’s conditional recommendation of spatial emanators – also known as spatial repellents – in combination with insecticide-treated nets, informed by Unitaid-backed research, marks a significant milestone in the fight against malaria. However, there is still a lack of evidence of its ability to protect against malaria as a standalone tool. To fill these research gaps CANVeCT will conduct a cluster randomised trial (RCT) of the SC Johnson Guardian emanator near Yaoundé, Cameroon, along with a trial in internally displaced persons camps in Eastern Cameroon. Clinical trials will be supported by entomology, social science activities, cost-effectiveness analysis and inform modelling efforts to produce tools to aid decision makers on the adoption of this new vector control tool.
Aug 2025 — Jul 2030
$18.14M
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