Last Updated: 27/02/2024
Mathematical analysis of models for the transmission dynamics of mosquito borne diseases
Objectives
The main aim of this research is to mathematically study three mosquito borne diseases in the presence of control, the diseases are Zika fever (this is because, in addition to the disease being transmitted vertically, it is the first mosquito borne disease known to be transmitted sexually), yellow fever (because despite having effective vaccine for the disease, it has continue to pose sporadic challenges in different regions of the world), and malaria (because it has the highest global burden among mosquito borne diseases despite continuous efforts to eradicate it).
Mosquitoes are long-legged, two winged flies that are responsible for the transmission of many diseases such as Zika fever, malaria, yellow fever, chikungunya and dengue hemorrhagic fever. Mosquito borne diseases account for substantial amount of para- sitic and infectious diseases, they have profound effects on economic growth of many developing countries. There have been continuous efforts to optimize and improve on existing mosquito control strategies, as well as to develop new tools aimed at reducing burden of mosquito borne diseases. Control strategies are either applied alone or in combination depending on available resources, education, health risk and burden of the disease. Some major highlights of the research include: Roles of mosquito vertical transmission in the transmission dynamics of mosquito borne diseases, and effects of incorporating human-human transmission are evaluated. Assessment of impact of using different control measures both in human and mosquito populations, and effects of controlling population of adult male (non-disease transmitting) mosquitoes through sterilization are conducted. Implication of incorporating aquatic stage of mosquito development in models for the transmission of mosquito borne diseases, as well as effect of temperature variation in the transmission dynamics of malaria are also studied.
Jan 2019
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