Last Updated: 03/05/2015
Evaluation of long-lasting microbial larvicides in reducing malaria transmission and clinical malaria incidence
Objectives
Rising insecticide resistance and increased outdoor transmission have greatly hampered the effectiveness of insecticide-treated nets (ITN) and indoor residual spraying (IRS) because the current indoor-based interventions do not target the outdoor-biting mosquitoes. Therefore, new supplemental interventions that can tackle outdoor transmission and pyrethroid insecticide resistance are urgently needed.
The central objective of this study is to determine the efficacy and cost-effectiveness of EPA-approved long-lasting microbial larvicides in reducing malaria transmission and clinical malaria incidence in western Kenya highlands.
ClinicalTrials.gov Identifier: NCT02392832
| Study Type : | Interventional (Clinical Trial) |
| Actual Enrollment : | 240000 participants |
| Allocation: | Randomized |
| Intervention Model: | Crossover Assignment |
| Masking: | Single (Participant) |
Derua 2018; Microbial larvicides for mosquito controlKahindi 2018; Efficacy and persistence of long-lasting microbial larvicides against malaria vectors in western Kenya highlandsZhou 2016; The impact of long-lasting microbial larvicides in reducing malaria transmission and clinical malaria incidence (protocol)
Apr 2015 — Sep 2019
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