WHO Calls for Data Submission: Entomological data to allow comparative assessment of insecticide-treated nets and indoor residual spraying products

In parallel with WHO’s move to a new evaluation process for vector control products, GMP revised its process for the development of recommendations and companion documents. This revised process provides better predictability, enhanced clarity on what malaria interventions are recommended and how they should be deployed, and supports uptake of guidance. One of the outputs of this process, the first edition of WHO’s consolidated Guidelines for malaria, was released in 2021 and has been updated and expanded since. A series of preferred product characteristics (PPC) documents were developed to communicate identified unmet public health needs and associated evaluation requirements. The present data call relates to the PPCs on insecticide treated nets (ITNs) and on indoor residual surface treatments (IRS).

WHO is rolling out the implementation of non-inferiority assessments of vector control products as an exploratory approach, drawing on entomological data (e.g. mosquito mortality, mosquito blood-feeding inhibition). To provide an update on the status of comparative evaluations conducted by manufacturers and researchers, WHO requests the submission of data packages that focus on ITNs treated with pyrethroid-PBO, pyrethroid-chlorfenapyr and pyrethroid-pyriproxyfen and on new insecticide classes for IRS not currently covered by WHO’s recommendation on IRS for malaria control.

Read more here.

Submission deadline May 1, 2023.