Wellcome Sanger Institute October Journal Club: Malaria Genomic Epidemiology

The Wellcome Sanger Institute is hosting the October Journal Club on Malaria Genomic Epidemiology.

Date: October 22, 2024

Time: 1.30 pm UK time

A recent pre-print offers the most comprehensive overview yet of kelch13 genetic markers, which are closely linked to artemisinin partial resistance (ART-R) in Plasmodium falciparum. Dr Andrew Balmer will delve into the findings from this review, which maps data from over 112,000 P. falciparum genome sequences worldwide to track kelch13 mutations, which are key markers of ART-R. By evaluating the spread of kelch13 mutations across different regions and over time, the review follows the emergence of ART-R in Southeast Asia and the concerning parallels now being seen in East and Northeast Africa. The authors also outline three potential scenarios for the future to help frame the trajectories of ART-R and its implications for malaria control efforts.

Speaker:

• Dr Andrew Balmer, Senior Data Scientist, Genomic Surveillance Unit, Wellcome Sanger Unit, UK.

To register please click here.