EDCTP Call for Proposals: Creating a sustainable clinical trial network for infectious diseases in sub-Saharan Africa

The European & Developing Countries Clinical Trials Partnership (EDCTP) on “Creating a sustainable clinical trial network for infectious diseases in sub-Saharan Africa” to support activities that are contributing to one or several of the expected impacts for this call. To that end, proposals under this topic should aim for delivering results that are directed towards and contributing to the following expected outcomes:

• A well-documented overview of operational and effective regional clinical trial and laboratory networks in different clinical settings in sub-Saharan Africa, and the existing coordination mechanisms within and between the networks, is developed;
• An efficient coordination and collaboration mechanism between identified clinical trial and laboratory networks in sub-Saharan Africa is established and sustained;
• The foundation for a coordinated, permanent, pan sub-Saharan African clinical trial infrastructure to optimise a coordinated response to infectious diseases threats, including emerging infections, is laid, taking advantage of the existing EDCTP’s Networks of Excellence;
• The role of Africa in clinical research preparedness for future epidemics and pandemics is strengthened.

Scope:

The work carried out under this topic should lay the foundation for the establishment of a pan sub-Saharan African infrastructure of clinical trial facilities that continuously evaluate health interventions (incl. vaccines, treatments and diagnostics) for infectious diseases in a coordinated, harmonized manner to maximize trial efficiency. Such an infrastructure should leverage the work done by EDCTP Networks of Excellence through interaction with these networks. It should also be capable of quickly and easily adapting ongoing clinical trials for vaccines, treatments or diagnostics to tackle emerging infectious disease threats, if and when the need arises.

The purpose of this topic is to support one project which will carry out a desk review and mapping exercise of the current landscape of clinical trial and laboratory networks in sub-Saharan Africa. Such an exercise would provide the basis for the creation of the intended network. The network could be composed of regional networks in Sub-Saharan Africa, each regional network with its connected clinical trial sites and laboratories. The structure to be built needs to ensure a harmonised approach to clinical trial implementation.

* Relevant regional and international organisations, such as the World Health Organization – Regional Office for Africa, the African Medicines Agency (AMA) or the Africa Centre for Disease Control and Prevention (Africa CDC), should be consulted when developing the plans for the future network.

Read more here.

Proposals deadline August 30, 2022.