EDCTP Call for Proposals: Tackling Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials

The European & Developing Countries Clinical Trials Partnership (EDCTP) is calling for proposals on “Tackling Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials”.

Proposals under this topic should aim to deliver results that are directed, tailored towards, and contributing to the following expected outcomes. Proposals need to address at least two of these, with the first bullet point being compulsory:

  • Improvement of the use of existing antimicrobials to reduce AMR and providing data contributing to their equitable access in sub-Saharan Africa, and/or the advancement of late-stage clinical R&D of novel antimicrobials with improved properties (efficacy, safety, resistance pattern, useability) in the clinical trials pipeline;
  • Data about development and implementation of antimicrobial stewardship (AMS) processes to optimise the use of antimicrobial medicines in human health and reduce antimicrobial resistance (AMR), employing the One Health approach;
  • Effective infection prevention control measures, sanitation and hygiene to reduce the need for and the use of antimicrobial medicines.

Scope:

Proposals must address at least two of the following areas, with the delivery of the first bullet point being compulsory:

  • Conduct R&D on the better use of existing antimicrobials to reduce AMR and provide data to contribute to their equitable access in SSA, and/or conduct late-stage clinical R&D on novel antimicrobials with improved properties (efficacy, safety, resistance pattern, useability) for infections within the scope of EDCTP3 to reduce AMR;
  • Develop innovative antimicrobial stewardship strategies in human health on how to tackle AMR based on the One Health approach within the scope of EDCTP3 in SSA;
  • Develop and implement cost effective, acceptable and feasible infection prevention and control (IPC) strategies, in reducing AMR in healthcare facilities and communities.

Funding details:

  • EUR 6 M per project

Read more here.

Proposal deadlines:

  • April 4, 2024
  • September 12, 2024.
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