EDCTP Call for Proposals: Research on existing Malaria vaccines and development of new promising candidates

The European & Developing Countries Clinical Trials Partnership (EDCTP) is calling for proposals on Research on existing Malaria vaccines and development of new promising candidates.

This topic aims at supporting activities that are contributing to one or several of the expected impacts for this call. Proposals submitted under this topic should aim at delivering results that contribute to at least two of the following expected outcomes:

Generating evidence required for accelerating registration of new vaccine candidates;
Generating long-term safety and efficacy data on currently registered vaccines;
Safety and efficacy results from other vaccines, especially those targeting all stages of plasmodium falciparum lifecycle, including promising candidates in phase 2a/b;
Generating evidence-based recommendations on how to boost manufacturing capacity and build an efficient supply chain for vaccines in general, and malaria vaccines in particular sub-Saharan Africa.

Scope:

Proposals submitted under this topic are expected to advance knowledge on the safety, efficacy and effectiveness of currently recommended malaria vaccines or new malaria vaccines. To this end, proposals submitted under this call topic should address at least two of the following:

Trials from Phase 2a should be considered, to ensure continuation of R&D on new generations of vaccines targeting all stages of plasmodium falciparum lifecycle;
Long term effectiveness studies through aligned primary endpoints should be considered where possible;
Collection, analysis and sharing of pharmacovigilance data on vaccines that are currently registered or candidates in late-stage efficacy trials.

Funding details:

EUR 15 M per project

EDCTP Call for Proposals: Research on existing Malaria vaccines and development of new promising candidates

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