Last Updated: 13/04/2026
Why is the hijacking of a human erythrocyte signalling pathway essential for malaria infection?
Objectives
This project aims to understand why human proteins are crucial for the parasite and to identify new human proteins hijacked by malaria.
Principal Institution
Principal Investigators / Focal Persons
Partner Investigators
Rationale and Abstract
Malaria drug resistance is spreading and the world needs cost-effective new drugs. Two human enzymes were found, known targets of cancer chemotherapy, to be key for parasite survival in red blood cells. This will open exciting options for antimalarial drug discovery: to harness funds invested in cancer drugs by targeting proteins with dual roles in cancer and malaria.
External reference
Themes
Date
Jan 2015 — Dec 2018
Total Project Funding
$372,217
Funding Details
National Health and Medical Research Council (NHMRC) Australia, Australia
Grant ID: 1082619
AUD 495,106
Country / Project Site(s)
Related Resources
