Last Updated: 11/07/2025
Unified understanding of the Plasmodium life cycle by Targetome analysis
Objectives
*Original title and text were machine translated from Japanese
This study analyzed the function of each Plasmodium transcription factor, identified its binding sequences, and determined target genes.
Rationale and Abstract
The results demonstrated the unique transcriptional regulation mechanism of Plasmodium parasites, in which a stage-specific transcription factor directly and comprehensively regulates genes and determines the gene expression repertoire at each stage. This project has also revealed the dynamic linkage of gene expression through the lifecycle by viewing it as a chain of targetomes.
External reference
Themes
Date
Apr 2017 — Mar 2020
Total Project Funding
$370,889
Funding Details
Project Site
Related Resources
