Last Updated: 02/10/2025
Understanding the role of an ancient fusogen in malaria parasite fertilisation and transmission
Objectives
The main goal of this project is to identify and characterize malaria parasite proteins essential for mosquito-stage fertilization, enabling the development of interventions that block transmission from mosquitoes to humans.
Walter and Eliza Hall Institute of Medical Research (WEHI), Australia
The global effort toward malaria elimination requires an array of tools to prevent, treat and block transmission of the malaria parasite. Blocking transmission involves targeting proteins that are essential for malaria parasite fertilisation in mosquitos, thereby preventing mosquito to human transmission. Understanding how these proteins work and discovering new fertilisation proteins is essential for developing effective interventions, like antibody treatments, to prevent transmission.
Feb 2025
$430,946
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