Last Updated: 15/05/2023

Targeting Plasmodium falciparum gametocytes

Objectives

To understand the biology of gametocytes and identifying new drug targets for transmission blocking strategies.

Principal Investigators / Focal Persons

Alice Butterworth

Rationale and Abstract

The transmission of malaria is dependent on gametocytes, the sexual stages of parasite development that are taken up by mosquitoes when feeding on an infected person. While gametocytes are not responsible for disease symptoms, it is clear that malaria eradication is not be possible without an understanding of their biology and the tools to prevent transmission. This research focuses on understanding the biology of gametocytes and identifying new drug targets for transmission blocking strategies.

Date

Jan 2012 — Dec 2015

Total Project Funding

$74,332

Project Site

Australia

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