Last Updated: 05/10/2023
Study of plasmodium-host interaction via meta-analysis of public data from dual RNA sequencing
Objectives
*Original title in Portuguese: Estudo da interação plasmodium-hospedeiro via meta-análise de dados públicos de sequenciamento duplo de RNA
To conduct a reanalysis of double RNAseq data from mammalian hosts infected by Plasmodium, as well as the integration of host-pathogen transcriptomes via new integration methodologies and perform a meta-analysis at the level of dual transcriptional networks to identify associations between Plasmodium-host that are conserved between different species, as well as associations that are species-specific.
This project will not only promote the advancement of knowledge about the biology of malaria, but it has the potential to identify unknown processes on the host immune response and/or mechanisms of Plasmodium evasion.
Apr 2021


