Last Updated: 05/10/2023

Study of plasmodium-host interaction via meta-analysis of public data from dual RNA sequencing

Objectives

*Original title in Portuguese: Estudo da interação plasmodium-hospedeiro via meta-análise de dados públicos de sequenciamento duplo de RNA

To conduct a reanalysis of double RNAseq data from mammalian hosts infected by Plasmodium, as well as the integration of host-pathogen transcriptomes via new integration methodologies and perform a meta-analysis at the level of dual transcriptional networks to identify associations between Plasmodium-host that are conserved between different species, as well as associations that are species-specific.

Principal Investigators / Focal Persons

Luiz Gustavo Araujo Gardinassi

Rationale and Abstract

This project will not only promote the advancement of knowledge about the biology of malaria, but it has the potential to identify unknown processes on the host immune response and/or mechanisms of Plasmodium evasion.

Date

Apr 2021

Project Site

Brazil

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