Last Updated: 25/07/2017

Researching how malaria parasites develop and become infectious in the mosquito vector

Objectives

The overarching goal of this project is to increase knowledge of mosquito biology and mosquito-Plasmodium interactions to contribute novel tools and concepts for malaria control. The aim is to perform molecular, genetics, biochemical, epidemiological and behavioural studies that will build on the current body of work to aid in the design and validation of innovative tools for the control of mosquito populations and malaria parasites.

Principal Investigators / Focal Persons

Flaminia Catteruccia

Rationale and Abstract

This project proposes to study the molecular and genetic mechanisms that shape the interplay between reproductive biology and Plasmodium development in Anopheles mosquitoes. The main focus is on how the malaria parasite exploits the physiological environment created by mating and blood feeding to achieve its own transmission. This work will be done in collaborations with experts in chemical ecology, tissue engineering, comparative genomics, microbiology, gene editing, mathematical modelling, and epidemiology. 

Date

Jan 2016 — Oct 2017

Funding Details
Gates Foundation (GF), United States

Howard Hughes Medical Institute-Gates Faculty Scholar
Project Site

United States

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