Last Updated: 17/12/2024
Reproducing Protection of Sickle Cells Against Malaria
Objectives
To test whether the protection against malaria seen in individuals with sickle cell anemia is caused by increased hemoglobin oxidation in sickle cells, and whether this can be transferred to healthy human blood cells to produce the same effect.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
Screening of the anti- malarial compounds in the Malaria Box for oxidative activity will determine if they could be used for malaria protection.
External reference
Date
Oct 2012 — May 2014
Total Project Funding
$100,000
Funding Details
Gates Foundation (GF), United States
Grand Challenges Explorations. New Approaches for the Interrogation of Anti-Malarial Compounds (Round 9)
Grant ID: OPP1069409
Project Site
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