Last Updated: 24/11/2025
Proguanil: Old Drug, New Tricks
Objectives
An exciting discovery has been made that an existing antimalarial drug can kill malaria parasites in a unique, previously unknown, manner. This project will investigate how this occurs and develop new drug candidates for malaria prevention.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
In 2013 there were ~200 million clinical cases of malaria, causing ~600,000 deaths. All antimalarial drugs are now associated with malaria parasite resistance. Thus, new therapies are urgently needed, including new drugs to prevent this disease.
External reference
Date
Jan 2016 — Dec 2018
Total Project Funding
$403,463
Funding Details
National Health and Medical Research Council (NHMRC) Australia, Australia
Grant ID: 1098848
AUD 536,517
Project Site
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