Plasmodium species co-infections in Anopheles mosquitoes: a pilot study of parasite-vector interactions that define transmission in Africa (CoMal)
Objectives
The objective of this project is to define the molecular interactions associated with Plasmodium development in African malaria vectors.
Principal Institution(s)
Principal Investigator
Project Outputs
Rationale and Abstract
Monitoring of drug resistance in Plasmodium populations is crucial for malaria control. This has primarily been performed in humans and rarely in mosquitoes where parasites genetic recombination occurs. Here, we characterized the Plasmodium spp populations in wild Anopheles vectors by analyzing the genetic diversity of the P. falciparum kelch13 and mdr1 gene fragments implicated in artemisinin and partner drug resistance across Cameroon in three major malaria vectors.
Thematic Categories
Date
2021 Jan - 2023 Dec
Total Project Funding
$346,082
Funding Details
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