Last Updated: 01/09/2025
Plasmodium falciparum mechanisms for erythrocyte invasion
Objectives
The main goals of the project are investigating variation in erythrocyte invasion mechanisms used by clinical isolates of the malaria parasite Plasmodium falciparum.
Principal Institution
Noguchi Memorial Institute for Medical Research (NMIMR), Ghana
Principal Investigators / Focal Persons
Rationale and Abstract
Plasmodium falciparum uses multiple redundant pathways for invading human red cells, and deploys invasion ligands strategically to evade host immune responses. Therefore, a better understanding of these mechanisms is crucial for identifying targets for a potential blood-stage vaccine for malaria.
Funding Details
Royal Society, United Kingdom
Grant ID: AA110050
World Bank, United States
Grant ID: ACE02-WACCBIP
Laboratory of Malaria and Vector Research (LMVR), NIAID/NIH, United States
Grant ID: R01AI102848
Project Site
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