Last Updated: 20/08/2024

Molecular mechanisms of gliding motility in Plasmodium merozoites

Objectives

*Original title and text were machine translated from Japanese.

This research focuses on the recently discovered “gliding movement” of malaria parasites used during the erythrocyte invasion stage, and works with overseas collaborators to investigate the gliding movement of malaria parasites in the erythroid stage through drug-induced gene knockout and interactome analysis to clarify molecules and their molecular mechanisms.

Principal Institution

Ehime University, Japan

Principal Investigators / Focal Persons

Kazuhide Yahata

Partner Institutions

Nagasaki University, Japan

Partner Investigators

Satoshi Yamanaka
Takaya Sakura

Rationale and Abstract

Plasmodium, the pathogen of malaria, is fatally pathogenic when it infects the host’s red blood cells, so by inhibiting red blood cell infection, it is possible to prevent parasite proliferation and suppress the disease.

Date

Oct 2022 — Mar 2025

Total Project Funding

$150,622

Funding Details
Project Site

Japan

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