Last Updated: 17/12/2024

Maximising the public health impact of interventions to control malaria in pregnancy through the translation of EDCTP-funded evidence-based global policies to country level policies and plans (IMPPACT)

Objectives

Overall Objective: To ensure the translation of WHO recommendations on malaria in pregnancy control policy resulting from the MiP Consortium’s research into country level policy and implementation plans.

Specific Research Objectives:

  1. Develop and make widely available a package of methodological tools that define optimal, cost-effective malaria in pregnancy interventions by drug resistance and transmission strata across sub-Saharan Africa using data from EDCTP-funded research;
  2. Advance optimal uptake of evidence-base through analysis of national level policy decision-making architecture and processes for the control of malaria in pregnancy to inform support in four selected countries, and evaluate the success of the policy change support processes as an exemplar to other countries;
  3. Provide expertise to support national policy change and preparation for implementation in the selected countries and ensure dissemination to policy stakeholders in the remaining trial countries;
  4. Maintain the MiP Consortium’s advocacy, networking, and dissemination functions and policy liaison activities with WHO.
Rationale and Abstract

Approximately 125 million women in malaria-endemic countries become pregnant every year, of whom over 85 million live in areas of Plasmodium falciparum malaria transmission. It has been estimated that, in areas of sustained transmission in sub-Saharan Africa in the absence of protection, infection in pregnant women would result in 900,000 preventable low birth weight (LBW) infants each year and the deaths of 200,000 new-borns and 10,000 mothers. These adverse outcomes can be substantially reduced by the use of highly cost effective interventions as recommended by WHO, including intermittent preventive treatment (IPTp) with sulphadoxine-pyrimethamine (SP), insecticide treated nets and case management of febrile illness and anaemia.

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