Last Updated: 01/12/2025
Manufacture and testing of clinical prototypes of magnetic blood filtration device to treat malaria
Objectives
This Pathfinder Award will enable MediSieve to develop clinical prototypes of the filter, and perform safety testing to demonstrate that the procedure does not cause any harm to healthy blood components. By the end of the project Medsieve aims to be in a position to apply for approval to perform clinical trials.
MediSieve is developing a novel magnetic blood filter device to treat malaria, with a focus on severe and drug-resistant patients. In a process similar to dialysis, a patient’s blood is continuously circulated through the device via an external blood loop. Malaria-infected cells are captured and removed by exploiting their naturally occurring magnetic properties, while the rest of the blood returns to the patient unaffected.
The magnetic blood filter can deliver a very rapid reduction in a patient’s infection burden to improve survivability and recovery times. It can be used as a standalone treatment for currently untreatable patients (drug resistant cases, pregnant women etc.), or in combination with drugs or order to improve their efficacy. By removing rather than killing infected cells, the magnetic filter avoids many of the undesirable side-effects of drug treatments.
Nov 2015 — Oct 2016
$140,793
Related Resources
