Last Updated: 27/05/2025
The intransigence of malaria in Malawi: understanding hidden reservoirs, successful vectors and prevention failures
Objectives
*Title between 2010-2016: Determinants of Malaria Disease in Malawi. Title in 2012: Determinants of Malaria Disease in Malawi, 5U19AIO89683, “Competitive Revision”.
Over the course of seven years of research, between 2017 and 2023, which will span Malawi’s next large national ITN distribution program, the Malawi ICEMR will identify why malaria control efforts in Malawi have been ineffective thus far and will provide data-driven suggestions regarding approaches that are more likely to be effective. Studies will be undertaken in three ecologically and epidemiologically different districts that span a range of transmission intensities. Analyses of changing transmission and disease will compare patterns before, during and after the nationwide ITN distribution program.
Successful malaria prevention, control and elimination activities depend on the sustained application of effective and well-targeted interventions. Developing innovative approaches and establishing novel applications of established approaches requires multi-disciplinary research. The research should be carried out in sites which span the ecological spectrum in which malaria thrives. Close coordination with policy makers enhances the transition from “data” to policy. Malawi, a landlocked country in southern Africa, is the ideal setting for transformative malaria research. Malawi contains within its boundaries nearly all of the eco-geographic settings relevant to malaria control. Malaria research in Malawi has been ongoing for over 20 years, and is concentrated in its one medical school, the University of Malawi College of Medicine. The National Malaria Control Program, the relevant policy-making body in Malawi, has made a series of data driven decisions, and its link with investigators in the College of Medicine is strong.
Jul 2017 — Mar 2024
$10.75M
