Last Updated: 12/11/2025
Individual-Based Modeling of Antimalarial Resistance & Control
Objectives
To use mathematical modelling approaches to understand the emergence of antimalarial drug resistance, including in the context of multiple first-line therapies.
Article: Slowing the spread of treatment failure to artemisinin-based combination therapies in UgandaArticle: Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletionsArticle: Effects of recombination on multi-drug resistance evolution in Plasmodium falciparum malariaArticle: Role of seasonal importation and genetic drift on selection for drug-resistant genotypes of Plasmodium falciparum in high-transmission settingsArticle: Assessing emergence risk of double-resistant and triple-resistant genotypes of Plasmodium falciparumArticle: National-scale simulation of human movement in a spatially coupled individual-based model of malaria in Burkina FasoArticle: Breaking the cycle of malaria treatment failureArticle: Pre-existing partner-drug resistance facilitates the emergence and spread of artemisinin resistance: a consensus modelling studyArticle: Long-term effects of increased adoption of artemisinin combination therapies in Burkina Faso
Apr 2020 — Sep 2023
$750,000
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