Last Updated: 08/07/2025

Immune surveillance of the CNS during malaria infection

Objectives

This project will investigate the mechanisms of CNS injury and provide fundamental information about T cell responses in the CNS during infection.

Principal Investigators / Focal Persons

Scott Mueller

Rationale and Abstract

Infections in the central nervous system (CNS) can have profound neurological complications. Neurological disease caused by cerebral malaria (CM) is a lethal complication in humans. A new model of longitudinal imaging of T cell responses have been established in the brain during experimental CM in mice infected with Plasmodium berghei ANKA.

Date

Jan 2017 — Dec 2019

Total Project Funding

$454,730

Project Site

Australia

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