Epidemiology Study of Malaria Transmission Intensity in Africa

This study is a multicenter epidemiology study at centers that are participating in GSK’s pivotal Phase III candidate malaria vaccine 110021 (NCT00866619) trial and will involve 4 annual cross sectional surveys performed preferably at peak transmission.

NCT01190202

Study type: Interventional
Study design: Intervention Model: Single Group Assignment
Intervention: 

• Procedure: Blood sampling (Capillary blood samples collected by finger/heel prick)
• Procedure: Assessment of body temperature (Assessment of axial body temperature with a digital thermometer)

Actual enrollment: 21618
Inclusion Criteria:

• Subjects who the investigator believes that they and/or their parent(s)/Legally Acceptable Representative(s) can and will comply with the requirements of the protocol.
• A male or female 6 months or older at the time of the survey.
• Written informed consent obtained from the subject/from the parent(s)/ Legally Acceptable Representative(s) of the subject.

Exclusion Criteria:

• Child in care.
• Previous or current participation in any malaria vaccine trial.

Clinical Trials Registration

Measurement of Transmission

Mar 2011 — Dec 2013

Burkina Faso
Gabon
Ghana
Kenya
Malawi
Tanzania