Last Updated: 02/06/2025
Dynamics of insecticide resistance in Anopheles funestus
Objectives
The main aim of this projects is to characterise the major malaria vectors from the Sudano-Sahelian regions of sub-Saharan Africa, to establish their contribution toward malaria transmission, and elucidate the features of insecticide resistance.
Specific objectives are to:
1. establish the distribution of the major malaria vectors from Sudano-Sahelian region, their seasonality and vectorial capacity
2. characterise insecticide resistance and cross-resistance status of the mosquito populations, identify potential synergists and candidate resistance genes
3. identify the major genes responsible for metabolic resistance, and discover molecular markers of the resistance to detect and track it in the field.
Liverpool School of Tropical Medicine (LSTM), United Kingdom
Malaria still devastates the tropical world; with a quarter of overall estimated mortality (~438,000 deaths) occurring in Nigeria alone. Achievement of 90% reduction in malaria cases and death by 2030 requires significant progress in control of the disease in Nigeria, and other neighbouring countries, such as Niger, Cameroon and Chad. The disease dynamics, i.e. composition and distribution of the malaria vectors, dynamics of malaria transmission and profiles of insecticides resistance and factors driving is poor characterised in the Sudano-Sahelian regions of these countries. Understanding the bionomics of the malaria vectors from these regions is indispensable to malaria control and elimination.
Oct 2016 — Mar 2024
$367,174
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