Last Updated: 13/04/2026
Development of synthetic gene drives using small molecules
Objectives
This project aims to use tools and principles of chemistry to develop controllers that will allow understanding of the strength and limitations of the gene drive technologies.
Principal Institution
Principal Investigators / Focal Persons
Partner Investigators
Rationale and Abstract
Gene drives enable a super-Mendelian inheritance where the chance of passing on the gene to the progeny is 100%, and this super-Mendelian inheritance has been demonstrated for several engineered genes in multiple organisms. Gene-drive mediated trait propagation in the entire ecosystem may find use in the elimination of diseases (e.g., malaria, dengue fever) or invasive species, and reversing the pesticide resistance in plants.
External reference
Date
Sep 2019 — Jan 2024
Total Project Funding
$1.43M
Funding Details
Country / Project Site(s)
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