Last Updated: 02/09/2025

Comprehensive investigation and functional analysis of endogenous viruses and endogenous viral elements in hematophagous arthropods and their host animals

Objectives

To examine endogenous viruses in ticks and mosquitoes and investigate their roles in nature under the “dance floor” hypothesis.

Principal Institution

Hokkaido University, Japan

Principal Investigators / Focal Persons

Hirofumi Sawa

Rationale and Abstract

Blood-sucking arthropods, such as mosquitoes and ticks, have been studied as vectors of pathogens, including zoonotic viruses.In this study, we examined especially endogenous viruses in ticks and mosquitoes and investigated their roles in nature under the “dance floor” hypothesis; in blood-sucking arthropods, their indigenous microorganisms and those from human or animal blood are communicating each other. As a result, we have discovered new endogenous viruses in the mosquitoes and ticks collected worldwide and found that these viruses may have co-evolved with their hosts.

Date

Jun 2016 — Mar 2021

Total Project Funding

$1.1M

Funding Details
Country / Project Site(s)

Japan
Sudan

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