Last Updated: 10/06/2024

Anti-malarial compounds that target the cytostomal endocytic pathway

Objectives

To identify anti-malarial compounds from the Malaria Box that function as inhibitors of the cytostomal endocytic pathway used by the malaria parasite P. falciparum to internalize host erythrocyte proteins.

Principal Institution

Virginia Tech, United States

Principal Investigators / Focal Persons

Michael Klemba

Rationale and Abstract

Characterizing the molecular mechanisms of this process could lead to the discovery of new anti-malarial compounds.

Date

Oct 2012 — Apr 2015

Total Project Funding

$100,000

Funding Details
Gates Foundation (GF), United States

Grand Challenges Explorations. New Approaches for the Interrogation of Anti-Malarial Compounds (Round 9)
Grant ID: INV-007252
Country / Project Site(s)

United States

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