Last Updated: 17/12/2024

Analysis of programmatic Mass Drug Administration for malaria in Zambia

Objectives

To assess the short-term impact of programatic Mass Drug Administration (pMDA) on the incidence of confirmed malaria cases, using routine data collected at health facilities and by community health workers in a low transmission province in Zambia.

Principal Institution

PATH, United States

Principal Investigators / Focal Persons

Caterina Guinovart

Rationale and Abstract

In 2016, the Zambian National Malaria Elimination Centre started pMDA campaigns with dihydroartemisinin-piperaquine as a malaria elimination tool in Southern Province. Two rounds were administered, 2 months apart (coverage 70% and 57%, respectively). We evaluated the impact of 1 year of pMDA on malaria incidence using routine data.

Study Design

Programmatic MDA was conducted in health facility catchment areas (HFCAs) with greater than 50 cases/1000 people per year. Ten HFCAs with incidence rates marginally above this threshold (pMDA group) were compared with 20 HFCAs marginally below (comparison group). 

Date

Nov 2016 — Nov 2017

Funding Details
Gates Foundation (GF), United States

OPP1134518 (Elimination Scale Up in Zambia)
Country / Project Site(s)

Zambia

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