Last Updated: 06/10/2025
Analysis of Plasmodium dense granules focusing on the heterogeneity of their endogenous proteins
Objectives
The main aim of this study is to clarify what proteins are contained in each dense granule (D)G and to elucidate the erythrocyte parasitism strategy of malaria parasites.
Elucidating the molecular mechanisms of how malaria parasites parasitize and grow in human erythrocytes is important for proposing new malaria treatment strategies. The representative is conducting research focusing on dense granules (DGs), unique intracellular organelles found in erythrocyte-invading malaria parasites. There are dozens of DGs in malaria parasites, all of which are observed morphologically to be similar. However, it is becoming clear that DGs can be classified into two or more types depending on the types of proteins present within them.
Apr 2025 — Mar 2028
$30,892
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