Last Updated: 08/10/2024

Abate: human-scented “trojan cows” kill vectors of disease

Objectives

To test whether an artificial lactic acid treatment (called abate) can trick disease-transmitting insects such as mosquitoes into infecting animals rather than their preferred human hosts, thereby reducing infection rates.

Principal Institution

ISCA Technologies, United States

Principal Investigators / Focal Persons

Agenor Mafra-Neto

Rationale and Abstract

Malaria-causing parasites are carried by mosquitoes, which identify the human hosts that help them reproduce by detecting the high levels of lactic acid in human perspiration. Cattle are resistant to malaria and many other human diseases transmitted by insects, and are often treated with deworming medication, which has a toxic effect on mosquitoes and their parasites. They will develop a stable formula of abate and test its effect on altering the host choice of several disease-transmitting insects to determine which is most effective.

Date

Apr 2014 — Oct 2015

Total Project Funding

$100,000

Funding Details
Gates Foundation (GF), United States

Grand Challenges Explorations. The One Health Concept: Bringing Together Human and Animal Health for New Solutions (Round 12)
Grant ID: OPP1106745
Project Site

United States

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