Last Updated: 29/09/2025
Search for mosquito factors and symbiotic microorganisms that determine malaria parasite transmission ability using samples collected from endemic areas
Objectives
This study aim to collect vector mosquitoes from the field in the Republic of Ghana, West Africa, where the infection is endemic, and to widely explore innate immunity-related molecules and symbiotic microorganisms that are negatively correlated with parasite infection through metagenomic analysis
Malaria is a mosquito-borne parasitic disease that infects 200 million people worldwide. In recent years, malaria control has faced difficulties due to the spread of vector mosquitoes resistant to multiple insecticides. The battle between malaria parasites and mosquito infection defense systems has been attracting attention, as it has been shown that malaria parasites are eliminated by innate immunity in some mosquitoes and that symbiotic microorganisms may be involved in their activation. The results obtained from this project can be used to develop new methods to block malaria transmission.
Sep 2024 — Mar 2028
$137,337
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