Last Updated: 18/06/2024
Signalling during red blood cell invasion by Plasmodium falciparum
Objectives
The aim of this project is to investigate if apical membrane antigen 1 (AMA1) plays a role in helping the parasite sense when it has contacted a blood cell and should invade.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
Malaria is one of the world’s most devastating infectious diseases and is caused by a parasite called Plasmodium falciparum. AMA1 is a parasite surface protein crucial for blood cell invasion but how it works is not understood. Discovering how parasites attach to and invade bloods cells is a priority for the development of anti-parasite drugs and vaccines
External reference
Themes
Date
Jan 2010 — Dec 2012
Total Project Funding
$355,568
Funding Details
National Health and Medical Research Council (NHMRC) Australia, Australia
Grant ID: 6733293
AUD 357,414
Project Site
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