Last Updated: 19/06/2024

The newly-discovered splenic Plasmodium reservoir as a target to reduce global malaria burden

Objectives

This study will use the world’s only collection of spleen and blood samples from untreated human infections, to study the splenic malaria reservoir, uncover its biology and identify new ways to improve malaria elimination strategies.

Principal Investigators / Focal Persons

Steven Kho

Rationale and Abstract

Recent discovery has been made that the spleen is the major reservoir for malaria parasites in natural human malaria infections. There are significant concerns that this previously-unrecognised reservoir underlies the major challenges faced to eliminate this disease.

Date

Dec 2022

Total Project Funding

$1.14M

Project Site

Australia

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