Efficacy of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy, Mansa, Zambia

Objectives

1) To determine the effectiveness of SP for IPTp as evaluated by pregnancy outcomes following IPTp; 2) To determine the efficacy of SP for IPTp in clearing peripheral parasitemia in asymptomatic pregnant women; 3) To characterize baseline resistance of P. falciparum to SP in select locations in Zambia using molecular markers; 4)To assess the relationship of therapeutic efficacy and SP for IPTp effectiveness with molecular markers for SP resistance.